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Publications

 

Prof. Dr. Herbert Riepl

2020

Urmann C. and Riepl H.” Semi-Synthetic Approach Leading to 8-Prenylnaringenin and 6-Prenylnaringenin: optimization of the Microwave-Assisted Demethylation of Xantohumol Using Design of Experiments” Molecules 2020, 25(17), 4007, https://doi.org/10.3390/molecules25174007

Ritter S., Urmann C., Herzog R., Glaser J., Bieringer S., Geisberger T., Wisenreich W. and Riepl H. “Where is Bacosine in Commercially Available Bacopa monnieri?” Planta Medica 2020, 86(8), 565-570. https://doi.org/10.1055/a-1137-4289

2019

Bieler L., Vogl M., Kirchinger M., Urmann C., Riepl H., Bandtlow C., Klimaschewski L., Aigner L., Couillard-Despres S., The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons, Frontiers in Cellular Neuroscience 2019, 13. https://doi.org/10.3389/fncel.2019.00332

2018

Venturelli S., Niessner H., Sinnberg T., Berger A., Burkard M., Urmann C., Donaubauer K., Böcker A., Leischner C., Riepl H., Frank J., Lauer U., Garbe C., Busch C. 6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells. C. Cell Physiol Biochem. 2018;51(2):543-556. doi: 10.1159/000495275.

2015

Kinzl, F. und Riepl, H.: Synthesis of Terpene Diamines Based on Camphor-Derived Dinitriles. Helvetica Chimica Acta 2015, 98(4) 447-452

Urmann C, Oberbauer E, Couillard-Després S., Aigner L, Riepl H: Neuro-differentiating Potential of 8 Prenylnaringenin and Related Compounds in Neural Precursor Cells and Correlation with Estrogen-like Activity. Planta Medica 2015; 81(4):305-311. doi: 10.1055/s-0034-1396243

2013

Oberbauer, E.*; Urmann, C.*; Steffenhagen, C.; Bieler, L.; Brunner, D.; Furtner, T.; Humpel, C.; Baeumer, B.; Bandtlow, C.; Couillard-Despres, S.; Rivera, FJ.; Riepl, H.; Aigner, L.; Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective; Journal of Nutritional Biochemistry; 24(11):1953-62; DOI:10.1016/j.jnutbio.2013.06.005.

Firlbeck, D.; Faulstich, M.; Urmann, C.; Tafesh, A.; Azaizeh, H.; Riepl, H.; Central Composite Design for Optimal Technology of Concentrating Vanillic Acid Using Foam Fractionation; Separation and Purification Technology; 119, 28-34; DOI:10.1016/j.seppur.2013.08.033

T. Huber, D. Firlbeck, H.M. Riepl, J.; Iridium-catalysed Isomerising Trialkylsilylation of Methyl Oleate; Journal of Organometallic. 744 (2013) 144-148; DOI: 10.1016/j.jorganchem.2013.06.002

2012

Herbert M. Riepl, Corinna Urmann,
Improved Synthesis of Indirubin Derivatives by Sequential Build-up of the Indoxyl Unit: First Preparation of Fluorescent Indirubines, Helvetica Chimica Acta.

2010

Herbert M. Riepl , Jürgen Pettrak, Martin Faulstich, Wolfgang A. Herrmann,
Self-metathesis of fatty alcohols and amines to provide monomers for polyester and polyamides, J. Macromol. Symp. 293, 39.

2009

Herbert M. Riepl and Melanie Kellermann:
Synthesis of Dibenzo[b,f][1,7]naphthyridine-6, 12-dion, an Unexpected Isolate from Isatis tintoria.
Helvetica Chimica Acta 2009, 92, 668

Buchbeitrag: Desmethylxanthohumol from Hops, Chemistry and Biological Effects; Reinhard A. Diller, Herbert M. Riepl, Oliver Rose, Corazon Frias, Günter Henze, Aram Prokop; Beer in Health and Disease Prevention, 2009, 703-709; Chapter 71

2008

Patrick Jesse; Herbert M. Riepl; Thomas Wieder; Günter Henze; Aram Prokop:
A Synthetic Analogue of the Indigo Jeans Dye Tryptanthrin Induces Apoptosis In Vitro, Ex Vivo and in In Vivo in Pediatric Leukemia and Lymphoma Cells Sensitizing Malignant Cells to Cytostatic Drugs Via Downregulation of XIAP.
J. American Soc. of Hematology, 2008, 112(11) 910

Herrmann, Wolfgang A.; Rost, Alexandra M. J.; Tosh, Evangeline; Riepl, Herbert; Kuehn, Fritz E.:
Super absorbers from renewable feedstock by catalytic oxidation.
Green Chemistry (2008), 10(4), 442-446

Reinhard A. Diller; Herbert M. Riepl; Oliver Rose; Corazon Frias; Günter Henze and Aram Prokop:
Desmethylxanthohumol from hops, chemistry and biological effects.
Buchbeitrag, Enzylopaedic Handbook of Hop and Beer

2007

Diller, R. A.; Riepl, H. M.; Rose, O.; Frias, C.; Henze, G.; Prokop, A.:
Ability of Prenylflavanones Present in Hops to Induce Apoptosis in a Human Burkitt Lymphoma Cell Line.
Planta Medica, 2007, Band 73, S. 755-761

2005

Diller, R. A.; Riepl, H. M.; Rose, O.; Frias, C.; Henze, G.; Prokop, A.:
Synthesis and Activity of Desmethylxanthohumol, a new potent apoptosis inducing agent from hops.
Chemistry & Biodiversity, 2005, 2, 1331

2004

Doll K.; Riepl H.; Dirksen G.: Pathophysiological significance of steatorrhea as well as of hydroxystearic acids in the feces of calves with diarrhea. Dtsch Tierarztl Wochenschr. 2004 Jan;111(1):22-8. German. PMID: 14983751, PubMed – indexed for MEDLINE, Related citations

1999

Doll K, Riepl H, Eichhorn W, Dirksen G.: Bile acid concentrations in serum, bile and feces of healthy calves and calves with diarrhea.  Dtsch Tierarztl Wochenschr. 1999 Jan;106(1):35-40. German. PMID: 10028759, PubMed – indexed for MEDLINE, Related citations

1993

Herrmann, W. A. H.; Anwander, R.; Riepl, H.; Scherer, W.; Whittaker, C. R.:
General synthesis and metal complexes of fused-ring bicyclic cyclopentadienes
Organometallics 1993, 12, 4342

1990

Herrmann, W. A. H.,;Kellner, J.; Kulpe, J.; Riepl, H.:
Water-soluble metal complexes and catalysts. 1. Water-soluble metal complexes of the sulfonated
triphenylphosphine TPPTS: preparation of the pure complex and its use as a catalyst.
Angew. Chem., 1990, 102, 408

Herrmann, W. A. H.; Kellner, J.; Riepl, H.:
Water soluble metal complexes and catalysts. III. New water soluble metal complexes of sulfonated
triphenylphosphine (TPPTS): Mn, Fe, Ru, Co, Rh, Ir, Ni, Pd, Pt, Ag, Au.
Journal of organometallic chemistry, 1990, 389, 103

Patente

2012

Riepl H. & Urmann C.
Refining process for separation of prenylated polyphenols
DE 102012105613 A1

2011

Aigner L.; Oberbauer-Hofmann, E., Couillard-Despres S., Rivera F., Riepl H., Urmann C., Biendl M.; Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders; PCT Int. Appl. (2012) WO 2012172090 A1 20121220

2004

EP2004/003467
H. Riepl; A. Prokop; T. Weder:
8-Nitrotryptanthrine and other tryptanthrine derivatives useful in the therapy of
neoplastic disease caused by hyper-proliferative cells, PCT-applied paten

1995

EP 95108100.9
Kellner, J.: Kulpe, J.; Riepl, H.; Herrmann, W.A.H.:
Sulfonated triphenylphosphane containing metal complexes

1993

EP 93112056.2
Winter, A.; Küber, F.; Spaleck, W.; Riepl, H.; Herrmann, W.A.H.; Dolle, V.; Rohrmann, J.:
Methods for preparation of olefin polymers by using zirconocenes with substituted indenyls

EP 93112057.0
Winter, A.; Rohrmann, J.; Antberg, M.; Spaleck, W.; Riepl, H.; Herrmann, W.A.H.:
Methods for preparation of olefin polymers by using special zirconocenes

1991

EP 91120843.7
Riepl, H.; Herrmann, W.A.H.; Rohrmann, J.:
Metallocenes with bicyclic cyclopentadienyl derivatives, methods for their preparation, use as catalysts for olefin
polymerisation

1989

EP 89121708.5
Kulpe, J.; Riepl, H.; Herrmann, W.A.H.; Kellner, J.:
Sulfonated triphenylphosphane containing metal complexes

Dr. Corinna Urmann
  • Urmann C. and Riepl H.” Semi-Synthetic Approach Leading to 8-Prenylnaringenin and 6-Prenylnaringenin: optimization of the Microwave-Assisted Demethylation of Xantohumol Using Design of Experiments” Molecules 2020, 25(17), 4007, https://doi.org/10.3390/molecules25174007
  • Ritter S., Urmann C., Herzog R., Glaser J., Bieringer S., Geisberger T., Wisenreich W. and Riepl H. “Where is Bacosine in Commercially Available Bacopa monnieri?” Planta Medica 2020, 86(8), 565-570. https://doi.org/10.1055/a-1137-4289
  • Bieler L., Vogl M., Kirchinger M., Urmann C., Riepl H., Bandtlow C., Klimaschewski L., Aigner L., Couillard-Despres S., The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons, Frontiers in Cellular Neuroscience 2019, 13. https://doi.org/10.3389/fncel.2019.00332
  • Venturelli S., Niessner H., Sinnberg T., Berger A., Burkard M., Urmann C., Donaubauer K., Böcker A., Leischner C., Riepl H., Frank J., Lauer U., Garbe C., Busch C. 6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells. C. Cell Physiol Biochem. 2018;51(2):543-556. doi: 10.1159/000495275.
  • Lüscher S., Urmann C., Butterweck V.Effect of Hops Derived Prenylated Phenols on TNF-α Induced Barrier Dysfunction in Intestinal Epithelial Cells. Journal of Natural Products 2017; (80)4: 925-931; DOI: 10.1021/acs.jnatprod.6b00869
  • Kirchinger M., Urmann C., Bieler L., Couillard-Despres S.,  Riepl H. B-Ring Modification in Prenylflavonoids of Hops and the effect on indution of neuronal differentiation. Planta Medica 2016; 82(S 01): S1-S381; DOI: 10.1055/s-0036-1596764
  • Lüscher S., Urmann C., Riepl H., Butterweck V. Effects of hops derived prenylflavonoids on TNF-α induced barrier dysfunction in intestinal epithelial cells. Planta Medica 2016; 82(S 01): S1-S381; DOI: 10.1055/s-0036-1596115
  • Urmann C., Oberbauer E., Couillard-Despres S.., Aigner L., Riepl H.: Neuro-differentiating Potential of 8‑Prenylnaringenin and Related Compounds in Neural Precursor Cells and Correlation with Estrogen-like Activity. Planta Medica 2015; 81(4):305-311; DOI: 10.1055/s-0034-1396243
  • Urmann C., Kirchinger M., Bieler L., Couillard-Despres S., Aigner L.,  Riepl H. Strucural Modification of Xanthohumol C and the Effect on Inducing differentiation in neural precursor cells. Planta Medica 2015; 81 – SL5C-05; DOI: 10.1055/s-0035-1565357
  • Firlbeck, D., Faulstich, M., Urmann, C., Tafesh, A., Azaizeh, H., Riepl, H. Central Composite Design for Optimal Technology of Concentrating Vanillic Acid Using Foam Fractionation. Separation and Purification Technology 2013; 119, 28-34; DOI:10.1016/j.seppur.2013.08.033
  • Oberbauer, E.*; Urmann, C.*; Steffenhagen, C.; Bieler, L.; Brunner, D.; Furtner, T.; Humpel, C.; Baeumer, B.; Bandtlow, C.; Couillard-Despres, S.; Rivera, FJ.; Riepl, H.; Aigner, L.; Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective; Journal of Nutritional Biochemistry; 2013, 24(11):1953-62; DOI:10.1016/j.jnutbio.2013.06.005.
  • Urmann, C., Oberbauer, E., Aigner, L., Riepl, H. New approach to large scale isolation of rare prenylflavonoids; Planta Medica 2013; 79 PJ49; DOI: 10.1055/s-0033- 1352253
  • Urmann, C.; Oberbauer, E.: Aigner, L.; Riepl, H. Neurogenesis-inducing flavonoids: A structure-activity study; Planta Medica 2013, 79 SL 50; DOI:10.1055/s-0033-1351876
  • Riepl H., Urmann C. Improved Synthesis of Indirubin Derivatives by Sequential Build-up of the Indoxyl Unit: First Preparation of Fluorescent Indirubins. Helvetica Chimica Acta 2012, 95(8): 1461-1477; DOI: 10.1002/hlca.201200042.
  • Urmann C., Oberbauer E., Aigner L. and Riepl H.: Differentiation Effects of Prenylflavanones and Chalcones Present in Hops in Neuronal Tissue Cultures; Planta Medica, 2011, 77 – SL52; DOI: 10.1055/s-0031-1282175

* Authors contribute equally

Patente:

  • Riepl H. & Urmann C. Refining process for separation of prenylated polyphenols DE 102012105613 A1
  • Aigner L.; Oberbauer-Hofmann, E., Couillard-Despres S., Rivera F., Riepl H., Urmann C., Biendl M.; Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders; PCT Int. Appl. (2012) WO 2012172090 A1 20121220
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Contact

Professorship Organic Analytical Chemistry

Schulgasse 16
D-94315 Straubing

Head

Prof. Dr. Herbert Riepl

Phone: +49 (0) 9421 187-302
Fax: +49 (0) 9421 187-285
Mail: herbert.riepl@hswt.de

Team Assistant

Roswitha Karl

Phone: +49 (0) 9421 187-221
Fax: +49 (0) 9421 187-285
Mail: roswitha.karl@hswt.de